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Ethnic difference in ovarian ageing between Caucasian and Indian women

Indian women, beware. Your biological clock is ticking an alarming six years faster as compared to your Caucasian counterparts.

A study conducted on ‘Ethnic difference in ovarian ageing between Caucasian and Indian women’ has revealed that the biological clock is running six years ahead in Indian women as compared to Spanish women.

The study will be presented at the conjoint meeting of International Federation of Fertility Societies and American Society for Reproductive Medicine in Boston, US.

“Caucasian women have good ovarian reserves even at 40 years while in Indian women they start declining at age 33-34. This finding is significant especially in the current scenario where many local women, following in the footsteps of their western counterparts, opt to marry late and postpone having a child for careers. Unfortunately, Indian women can ill-afford this luxury,” said fertility specialist Dr Manish Banker.

The biological clock refers to the women’s fertility which is decided by their ovarian reserves. Each woman is born with a certain number of ovaries which are released during monthly cycles. When the reserve ends, the woman hits menopause.

In the study, the differences in ovarian reserve markers and ovarian response between 465 age-matched Indian and Caucasian women were studied. For this, women below 43 years of age undergoing IVF treatment for non-ovaries-related infertility — including the husband having low sperm count and malfunctioning fallopian tubes — were covered.

In all, 236 women taking treatment in Ahmedabad and Delhi and 229 women undergoing treatment in Madrid and Valencia in Spain were studied. “There is a possibility that Indian women have specific genes which makes their biological clock tick faster. This could also be dependent on the lifestyle of Indian women, including diet and exercise, as compared to their western counterparts. We will now undertake genetic and other studies to find out specific reasons,” says Dr Banker.

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